
Isoxsuprine hydrochloride
CAS No. 579-56-6
Isoxsuprine hydrochloride( —— )
Catalog No. M15128 CAS No. 579-56-6
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
Purity : >98% (HPLC)






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200MG | 45 | In Stock |
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Biological Information
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Product NameIsoxsuprine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
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DescriptionA beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor. (In Vitro):Results show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60?μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin).(In Vivo):Total infarct volume in vehicle-treated animals is 279±25 mm3 compare to 137±18 mm3 in Isoxsuprine hydrochloride-treated animals.
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In VitroResults show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60?μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin).
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In VivoTotal infarct volume in vehicle-treated animals is 279±25 mm3 compare to 137±18 mm3 in Isoxsuprine hydrochloride-treated animals.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAdrenergic Receptor
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Recptorβ-adrenergic receptor
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number579-56-6
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Formula Weight337.84
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Molecular FormulaC18H24ClNO3
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESCl.CC(COC1=CC=CC=C1)NC(C)C(O)C1=CC=C(O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gozo EG Jr, Yebes RB. Chest. 1984 Nov;86(5):736-40.
molnova catalog



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